Postdoctoral Scientist- Boiko Lab

Several Postdoctoral positions in the areas of cancer cell biology and cancer immunotherapy are available immediately in the Boiko lab at the department of Medicine, Cedars Sinai. The Candidate will participate in the NIH funded projects investigating strategies to target critical signaling pathways and immune checkpoints in melanoma and other solid tumors. These projects will entail molecular biology approaches using cloning, shRNA and CRISPR techniques, in-vitro proliferation and activation assays of patient derived tumor cells and the immune cell lineages (including but not limited to Macrophages and T-Cells), generation of monoclonal and bi-specific blocking antibodies/peptides. Many of these studies will involve genetic and xenografted tumor models in mice. Applicants who have recently obtained a PhD and have experience in the areas listed above are especially encouraged to apply. A separate group of projects will involve system biology approaches to analyze gene expression and sequencing data at the tissue and single cell level to unravel molecular evolution of tumor progression and identify novel critical gene targets. Recent PhD graduates with solid bioinformatics background are encouraged to apply for these projects.Successful applicants will have a strong record of productivity and manuscript writing, will possess passion and self-motivation for scientific discovery and be able to work effectively as a team member.In addition the postdoctoral scientist will also be responsible for the following:

The postdoctoral scientist will perform routine and complex laboratory procedures throughout training period in the field of cancer biology.

May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data.

May assist in preparation of grant proposals. Responsible for designing experiments, assembling data for publications and presentations as author or co-author. Not responsible for generating grant funds.

Responsible for the designe of experiments in cooperation with the mentor.

Responsible for compiling figures and text for the submission of publications and presentations as author or co-author.

Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the mentor.

Operates and maintains equipment and instruments.

Educational Requirements

Doctorate Degree - Doctorate (MD, PhD, VMD, or DDS) in in biomedical sciences, pharmacology, or an area directly related to field of research specialization, with demonstrable laboratory experience in drug discovery and natural products research, and in vivo mouse models for antitumor efficacy and pharmacology.

Work Experience

Works independently on research projects designed by a mentor (typically the PI) within area of specialization.

Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.

Experience as a first author in one or more publications on impactful body of work.

Demonstrable laboratory experience (1-4 years) in drug discovery and natural products research, in vivo mouse work, antitumor efficacy, and pharmacology, with some experience in molecular biology, tumor cell biology, microbiology, and protein purification and production.

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.