Senior Research Associate - Cell Culture Process Development

The Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best in class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products. This organization encompasses vector and cell line engineering, upstream and downstream process development, analytics, and clinical manufacturing support. The cell culture process development group is responsible for viral vector production optimization and development of next generation production platforms to support high dose therapeutic products. The group is seeking a motivated Senior Research Associate to join the team. Key Responsibilities

Support the executionand data analysis for viral vector productionprocess development experiments

Work with risk group 2 infectious materials, follow safe lab procedures and maintain good laboratory practices (GLPs)

Contribute to technical reports and protocols

Support maintenance of facility infrastructure and management of assay reagent, control and standard inventories, as well as other support requirements

Collaborate with team to identify areas for improved operational excellence

Stay updated on new, relevant technologies and published literature to support innovation within the group

Support new technology evaluations to increase product yield and process understanding

Independently, manage personal training schedules as per established procedures

Communicate effectively with teams

Display sound technical judgement

Perform weekend and holiday work to support on-going lab activities

Basic Qualifications   

Master’s degree in biological science engineeringor relateddiscipline or a Bachelor’s degreewith a minimum of 2 years of relevant experience in the life sciences, biotechnology or pharmaceutical industry

Aseptic skills as demonstrated by experiences with a variety of cell line maintenance and expansion.

Understanding of mammalian cell culture processes (thaw to production)

Knowledge and understanding of cell culture and viral vector production systems

Understanding of key test performance indicators, monitoring and trending of data

Ability to stand and work with lab bench equipment

Good organizational, record keeping, and communication skills

Motivated and self-directedwithcommitment to meetaggressive timelines

Team player, detailoriented and organized

Preferred Qualifications   

Understanding of viral process development concepts

Experience of bioreactor operations (including high-throughput reactors) and cell culture processes

Ability to work on multiple tasks simultaneously

Ability to work under moderate supervision and function within a collaborative/team-oriented environment

Knowledge of Design of Experiments (DoE’s) using JMP or equivalent software whileapplied to cell culture processes

At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce – and workplace – which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE.#GD-SA#LI-SAAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.