Lead Bioinformatics Scientist, GRC - 225263

Lead Bioinformatics Scientist, GRCJob ID225263LocationSchool of Medicine & DentistryFull/Part TimeFull-TimeFavorite JobRegular/TemporaryRegularOpeningFull Time 40 hours Grade 055 Functional GenomicsSchedule8 AM-4:30 PM; OCC WKND/HOLResponsibilitiesPOSITION SUMMARY:The Genomics Research Center (GRC) at University of Rochester Medical Center is looking for a highly motivated and creative Lead Bioinformatics Scientist to develop and apply innovative analytical approaches in the area of genomics. You will collaborate with University of Rochester and Wilmot Cancer Institute investigators to analyze data such as single-cell genomics, bulk RNA-seq, DNA methylation, CUT&RUN/CUT&TAG, ChIP- seq, ATAC-Seq, microbiome, virome, and microRNA-Seq to understand cancer cell biology, help the investigators prepare manuscripts and grant applications. You will also lead the evaluation of published bioinformatics tools and develop the optimized pipelines to share with the research community at University of Rochester. This role will aid in the supervision of the bioinformatics staff with the Genomics Research Center to ensure efficient use of computational resources, participate in collaborative projects, and offer mentorship to junior bioinformaticians. The GRC provides a highly interactive environment with collaborative opportunities across basic and clinical departments, access to high performance computing clusters, highly automated analytical pipelines and integration with high-throughput sequencing infrastructure to aid in experimental design and execution for delivery of high-quality results for highly competitive projects. Candidates with a strong background in bioinformatics, computational biology, machine learning are highly encouraged to apply for this position. This position is located in Rochester, NY and located within the Wilmot Cancer Institute. The Lead Bioinformatics Scientist will report directly to the Director of the Genomics Research Center (GRC) and will operate with minimal supervision.RESPONSIBILITIES:Analytical Support: Perform custom and complex NGS analyses, specifically single-cell genomics analyses. This will include active collaborations with faculty, bioinformaticians, and clinicians at URMC and other institutions. Write documentation and protocols for the research project(s). Analyze and evaluate experimental data and interprets results. Prepare written reports on all phases of work involved in research projects. Contribute to the design, interpretation and final writing of research publications – thereby meeting expectations for co-authorship of scientific publications.

Develop, design, and publish new software for genomic data analysis and contributes to writing of research proposals. Prepare regulatory documentation required for performance of research. This can be standalone or in collaboration with faculty, bioinformaticians, biostatisticians, and clinicians at URMC or other institutions. Keep abreast of trends in the field by reading current research literature, abstracting scientific articles, and attending and presenting at scientific meetings, seminars and research conferences.

Bioinformatics Operations: Supervise, manage, and develop a team responsible for GRC bioinformatics services. This includes reviewing deliverable materials prior to release, creative direction and evaluation of all GRC pipelines/workflows, project management to ensure deadlines are met in a timely manner and to oversee quality or work performed efficiently, stewardship of the GRC data archive, and mentorship of bioinformatics staff. (30%)

Proactively identify and evaluate new software for analysis of genomic data to maintain professional knowledge of current trends and developments in the field and work with staff to incorporate new methodology seamless into GRC workflows. (10%)

Community Education and Support: Participate in experimental design consultation meetings with GRC customers and provide education to the URMC community in the form of individual correspondence, seminars, and GRC sponsored workshops.

Address project specific questions or concerns from investigators regarding analyses or experimental design, as they emerge.

REQUIREMENTS:Bachelor’s degree in related discipline and 4-5 years of related experience, preferably 2-3 years in a supervisory capacity or an equivalent combination of education and experience. Master's degree in Bioinformatics with 7+ years of experience in analysis of high-throughput sequence data and experimental consulting for genomics applications, specifically in single-cell genomics preferred. Experience with multiple computer operating systems (Windows, Mac, Linux and Unix), computer languages (C, Java/Parallel Java, MySQL, Perl, Python and R) is essential. Excellent verbal and written communication skills required. How To ApplyAll applicants must apply online.EOE Minorities/Females/Protected Veterans/Disabled