22 Jan
Associate Scientist III, Technical Development
Massachusetts, Cambridge , 02138 Cambridge USA

Vacancy expired!

Job Description

The successful candidate will support development, optimization, qualification, execution and troubleshooting of various bioassays to characterize large molecule products (recombinant proteins and gene therapies).

Responsibilities:

  • The individual will develop, qualify and perform assays to measure levels of residual host cell protein impurities, target binding and functional potency for both innovator and biosimilar programs. They may also assist in the engineering of cell lines to support the development of cell-based functional assays.
  • Responsibilities include implementation of experiments, data analysis, accurate record keeping, report writing and reviewing, as well as delivering internal technical presentations. The individual will also be involved in new technology evaluations and implementation.

Qualifications

  • Strong experience with mammalian cell culture and immunoassays is required.
  • Previous work with AAV and lentivirus and hands-on experience in transgenic cell line generation and assay development and/or method troubleshooting is preferred.
  • Familiarity with molecular techniques (primer design, restriction digestion, DNA electrophoresis, PCR, etc), various detection technologies (fluorescence, luminescence, ECL, etc.), statistical analysis for biological assays and automation is desirable.
  • The ideal candidate is a fast learner with strong scientific curiosity, an attention for detail and good interpersonal skills. The individual must be able to work independently and as a part of a team.

Education:

B.S. with 2-4 years of experience or M.S. with 0-2 years of experience in Biochemistry, Biology, or related Biological Sciences. Candidates with industry experience preferred.

Additional Information

The successful candidate will support development, optimization, qualification, execution and troubleshooting of various bioassays to characterize large molecule products (recombinant proteins and gene therapies).

Vacancy expired!


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