22 Feb
Upstream Development Scientist
Massachusetts, Lexington , 02420 Lexington USA

Vacancy expired!

Job Description

  • Responsible for performing upstream process development, including timely completion of small-scale experiments, scale-up, technology transfer and GMP floor support for programs that bring new biopharmaceutical products to pre-clinical, clinical and process validation manufacturing phases.
  • Cell banking, cell expansion, bioreactor process, and harvest clarification process development, optimization, characterization, scale-up, and technology transfer to CMO’s and/or internal manufacturing facilities.
  • Participate in cell culture process development, scale-up, and technology transfer activities.
  • Applies basic knowledge from various technical areas, industry standards and practices, provides quality and productive output that is consistently timely, reliable and reproducible.
  • Provide technical support and apply knowledge and execute experiments toward development and optimization of cell culture processes and in line with overall project plan and milestones under close supervision.
  • Manage, operate, monitor, and troubleshoot bench-top bioreactors and related control systems.
  • Documents data accurately in laboratory notebooks and completely as per established company guidelines/SOPs.
  • Contributes to technical documents such as reports, protocols, internal presentations and regulatory filing documentation.
  • Participate in and contribute to team meetings, including sub-teams, project teams, tech. transfer teams, and departmental meetings.

Qualifications

  • BS (0-3 years) in Chemical/Biochemical Engineering/Biological Sciences or related discipline with relevant industry experience in upstream process development.
  • Proven record of technical proficiency and troubleshooting.
  • Proven ability to work in a fast-paced environment with demonstrated capacity to juggle multiple competing tasks and demands.
  • Have working knowledge and experience with mammalian cell culture process development, process scale-up, tech. transfer, and GMP manufacturing support
  • Have experience in design-of-experiment and the ability to analyze and interpret data collected
  • Embrace and demonstrate teamwork/collaboration and the ability to communicate appropriately and effectively in both oral and written format
  • Demonstrate ownership in executing bioreactor process development, tech. transfer, and manufacturing support
  • Have the ability to proactively learn new technologies and manage changes in bioreactor process development and process scale-up
  • Have experience working in GMP environment
  • Experience with mammalian cell culture, experienceworking specifically with CHO cells is preferred
  • Present issues and discussresults in group and team settings as needed.
  • Apply fundamental engineering and/or biological principles to practical technical challenges
  • Work closely with his/her supervisor and coworkers in managing projects.
  • Provide input into the development of new cell culture processes.

Additional Information

Position is full-time, Monday - Friday 8:00am - 5:00pm. Candidates currently living within a commutable distance of Lexington, MAare encouraged to apply.

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Vacancy expired!


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