Associate Scientist, Enzymology DMPK

Why Patients Need YouPfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.What You Will AchieveIn your role, you will be joining a dynamic group of scientists in the Enzymology section of ADME Sciences within the Department of Pharmacokinetics, Dynamics & Metabolism, supporting global Pfizer small molecule research and development portfolio. Your position will be responsible for conducting ADME (absorption, disposition, metabolism, and excretion) enzymology studies. You will have the unique opportunity to work with project representatives and influence the selection of candidate molecules for drug development.As an Associate Scientist, you will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge. You will work closely with your supervisor to conduct in vitro enzyme kinetics, drug-drug interaction studies, enzyme phenotyping, and coordinate in vivo PK submissions. You will also author internal study reports and research reports in support of regulatory submissions. Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines in our fast-paced environment.It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.How You Will Achieve It

Apply technical skills to complete assigned work within own work group/project team.

Provide quantitative analysis of drugs and metabolites from biological matrices by LC-MS/MS.

May use robotics and automation for screening compounds through established assays.

Maintain up to date electronic laboratory notebooks and records in accordance with Pfizer policy.

Collaborate with others in the ADME Sciences group to enable portfolio support, troubleshooting, and technology improvement/development.

Become proficient in utilizing internal software for data management as the recording of data via computer systems is critical and mandatory to adhering to laboratory standard operating procedures.

QualificationsMust Have

BS/MS degree in chemistry, biochemistry, biology, biomedical, pharmaceutical sciences or related field with 0 to 3 years of experience

Excellent computer, verbal and written communication skills.

Ability to work effectively in a team environment.

Nice To Have

Experience conducting in vitro assays and working in a lab.

DMPK (drug metabolism/pharmacokinetics) knowledge, cell culture experience, or LC-MS/MS operational experience.

Strong mathematical, analytical and reasoning skills.

Proficient in the use of Microsoft Office Suite of tools (Outlook, Word, Excel, etc.).

PHYSICAL/MENTAL REQUIREMENTS

The position will require the scientist to work in the laboratory, including standing, walking, sitting, and lifting solvents. It also requires ability to perform mathematical calculations and data analysis.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Some travel (a few times per year) may be required to other Pfizer sites.

Work Location Assignment: On Premise

The annual base salary for this position ranges from $54,700.00 to $91,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.Relocation assistance may be available based on business needs and/or eligibility.Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.EEO & Employment EligibilityPfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.Research and Development