05 May
Synthetic DNA Process Development Scientist
Kentucky, Louisville , 40201 Louisville USA

Position SummaryWe are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production.Key Responsibilities Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides  Process development and scale-up from R&D to manufacturing Develop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting) Troubleshoot synthesis and purification challenges to improve yield and purity Collaborate with manufacturing, QC, and engineering for process transfer Evaluate new chemistries and technologies Author SOPs, batch records, and technical reports Ensure compliance with quality systems Mentor lab technicians 


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