Senior Scientist Discovery Pharmaceutical Sciences

Job DescriptionSenior Scientist – Discovery Pharmaceutical Sciences (DPS)Site: South San Francisco (SSF), CAPosition DescriptionOur company's Scientists in Discovery Pharmaceutical Sciences (DPS) has the exciting opportunity to work on multi-disciplinary Discovery teams to help identify, characterize, and successfully transition quality compounds from discovery to development. Towards this end, DPS scientists:

Work closely with Medicinal Chemists to build key structure-property relationships across multiple drug modalities to identify optimal candidates for development; Emphasis on small molecules

Design enabling preclinical formulations (drug delivery) for pharmacology and toxicology studies

Optimize preclinical drug candidates’ solid state phase (stable polymorph ID, salt selection)

Deliver key data sets for development candidate evaluation (Developability Assessment).

Working at our company's Discovery Innovation Hub in South San Francisco, the candidate will represent DPS on discovery teams, carrying out the activities described above to progress compounds through all phases of discovery and their transition to development. The candidate should have a creative passion for identifying and executing on effective drug delivery technologies and pharmaceutics as well as a track record of driving results and rapidly progressing from idea conception to in-vitro & in-vivo testing. As part of our company's emphasis on innovation, the successful candidate also will actively explore and engage external (commercial and academic) opportunities for new technologies related to drug delivery and pharmaceutics. The candidate must excel in a team environment, where they also will collaborate with CMC development functions (preformulation, chemistry, formulation, analytical, and biopharmaceutics research) in order to translate early data sets to clinical formulation development and ultimately drug products.The candidate will be expected to effectively present their work at team meetings as well as promote our company's science through publications and presentations/lectures. The successful candidate must be able to balance their core laboratory research, team representation, and participation in key initiatives.The position reports to the local DPS team leader in SSF. The candidate will effectively collaborate with the Discovery Pharmaceutical Sciences team on the east coast in order to identify and advance programs and key departmental strategic and cultural initiatives. The candidate will be responsible for maintaining a safe DPS lab and driving improvements in daily lab experimentation.Position Qualifications:Education Minimum Requirement:

Ph.D. in pharmaceutical science, chemistry, or related science is highly preferred.

Preferred Experience and Skills:

0-8 years’ experience in a pharmaceutical preclinical development or discovery organization. Hands-on experience in drug delivery (i.e., Solubilization, nanoparticles, etc) and solid state phase characterization is highly preferred. Additional sub-specialty experience in biologics and parenterals is also desirable.

The successful candidate will have excellent leadership, interpersonal, communication, and collaboration skills along with strengths in delivering results on firm deadlines in support of discovery/development programs. Demonstrated disposition towards recognition in the field, creativity and innovation via a strong publication/presentation record is also highly desirable.

#eligibleforERPNOTICE FOR INTERNAL APPLICANTSIn accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separationpackage, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld)Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld)US and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088EEOCKnowYourRights1020.pdf)EEOC GINA Supplement​Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp%20EnglishformattedESQA508c.pdf)We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/)U.S. Hybrid Work ModelEffective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.Expected US salary range:$125,000.00 - $196,800.00Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here (https://www.benefitsatmerck.com/) .Search Firm Representatives Please Read CarefullyMerck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.Employee Status:RegularRelocation:DomesticVISA Sponsorship:YesTravel Requirements:No Travel RequiredFlexible Work Arrangements:Not ApplicableShift:1st - DayValid Driving License:NoHazardous Material(s):n/aJob Posting End Date:09/23/2024A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.Job Posting End Date: 09/23/2024A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.Requisition ID: R311209